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. 2016 Sep 2;7:12685. doi: 10.1038/ncomms12685

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Copyright © 2016, The Author(s)

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(a) Whole-mount images of K-MADM-p53 mice at various time points following lentiviral Cre administration displaying p53^KO/KO (green, GFP+/tdTomato-), p53^WT/WT (red, GFP-/tdTomato+) and p53^KO/WT (yellow, GFP+/tdTomato+) cells within lung tumours. p.i., post infection. (b) Lung adenocarcinomas consisting mostly of green cells. (c) Mixed-grade tumour consisting of adenoma (left) and adenocarcinoma cells (right). The adenocarcinoma component consists of all green cells. Blue, DAPI-stained nuclei. Scale bars, 200 μm (all).