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. Author manuscript; available in PMC: 2017 Sep 30.
Published in final edited form as: Psychiatry Res. 2016 Jul 19;255:24–34. doi: 10.1016/j.pscychresns.2016.05.009

Fig. 5.

Fig. 5

Figure illustrates the effect of cannabis exposure moderated by CNR1 variation. Analysis of the rs806368 and rs1049353 haplotype showed a significant interaction between the presence of any TA within this haplotype and cannabis exposure (F=7.08, df=2, 64.7, p=0.002). A linear model in which the number of TA variants was tested was also significant (F=4.97, df=2, 64.24, p=0.004). The rs806368 and rs1049353 are 3′ UTR variants that have been localized to exon 5 of the CNR1 gene.