Table 3.
Full sample (N=88) | ||||||
---|---|---|---|---|---|---|
Covariates=Familial risk, scan age, sex | ||||||
Voxel statistics |
Cluster statistics |
|||||
MNI coordinate (mm) | ||||||
x | y | z | Peak Z | puncorr | Size (k) | p(FWE) |
5 | 32 | 24 | 3.81 | <0.001 | 423 | 0.055 |
Non-smokers of cigarettes sample (N=63)a | ||||||
Covariates=Familial risk, scan age, sex, personal use of alcohol | ||||||
2 | 33 | 21 | 3.78 | <0.001 | 536 | 0.013 |
Non-smokers of cigarettes sample (N=57)b | ||||||
Covariates=Familial risk, scan age, sex, personal use of alcohol, prenatal alcohol exposure | ||||||
9 | 33 | 16 | 3.86 | <0.001 | 774 | 0.001 |
Non-smokers of cigarettes sample (N=54)c | ||||||
Covariates=Familial risk, scan age, sex, personal use of alcohol, prenatal alcohol exposure, prenatal drug exposure, prenatal cigarette exposure | ||||||
11 | 32 | 16 | 4.65 | <0.001 | 1347 | <0.001 |
MNI=Montreal Neurological Institute. FWE=Family Wise Error.
Voxel statistics refer to peak effects within a cluster. Cluster statistics reflects a greater number of contiguous voxels exceeding p < 0.005 (uncorrected) than expected by chance, after controlling for whole brain FWE.
15 smokers were removed from the analysis.
Data concerning prenatal alcohol exposure was not available for 6 cases.
Data concerning prenatal exposure to drugs and cigarettes were not available for an additional 3 cases.