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. 2016 Sep 16;6:33327. doi: 10.1038/srep33327

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Phylogenetic tree based on the reference genomes of 333 JCV strains. The genomes from the BKV+ (red) and BKV− (blue) subjects are intercalated into the circular dendograms. The evolutionary history of the virus strains was inferred by the maximum likelihood method based on the Tamura-Nei model. The bootstrap consensus trees were inferred from 100 replicates that represent the evolutionary history of the virus taxa. Branches corresponding to partitions reproduced in less than 50% bootstrap replicates are collapsed. SA12 (simian agent 12, a baboon polyoma virus) was used as an out group. The tree is drawn to scale, with branch lengths measured in the number of substitutions per site. Samples analyzed in the study are labelled as - sample name/isolate name.