Table 2.
Experimental vs. predicted (Eq. 9) Sw values.
| Drug | Sw, mg/ml (log) Experimental | Sw, mg/ml (log) Predicted | Error (log) | Absolute Error (log) |
|---|---|---|---|---|
| Alprazolam | 0.10 (−1.00) | 0.11 (−0.96) | 0.04 | 0.04 |
| Amoxicillin | 2.47 (0.39) | 2.15 (0.33) | −0.06 | 0.06 |
| Ampicillin | 7.85 (0.89) | 1.14 (0.06) | −0.84 | 0.84 |
| Caffeine | 22.0 (1.34) | 21.3 (1.33) | −0.01 | 0.01 |
| Carbamazepine | 0.13 (−0.90) | 0.24 (−0.62) | 0.29 | 0.29 |
| Doxycycline | 1.80 (0.26) | 0.97 (−0.01) | −0.27 | 0.27 |
| Fluconazole | 3.56 (0.55) | 15.2 (1.18) | 0.63 | 0.63 |
| Lamivudine | 84.9 (1.93) | 65.6 (1.82) | −0.11 | 0.11 |
| Mercaptopurine | 0.12 (−0.93) | 0.05 (−1.33) | −0.40 | 0.40 |
| Myricetin | 0.00 (−3.19) | 0.00 (−2.89) | 0.30 | 0.30 |
| Phenobarbital | 1.21 (0.08) | 3.45 (0.54) | 0.46 | 0.46 |
| Piroxicam | 0.01 (−1.91) | 0.01 (−1.83) | 0.08 | 0.08 |
| Stavudine | 90.6 (1.96) | 11.5 (1.06) | −0.90 | 0.90 |
| Theophylline | 6.75 (0.83) | 6.14 (0.79) | −0.04 | 0.04 |
| Average | −0.06 | 0.32 |