TABLE II.

Muscle Morphology in Biopsies as Assessed by Immunohistochemical Analyses

	Uninjured Limb*	Injured Limb Before Surgery*	P Value	Injured Limb After Surgery*	P Value†
Type-I fibers/total fibers	0.44 ± 0.11	0.48 ± 0.18	0.53	0.40 ± 0.20	0.20
Type-I fiber CSA (μm2)	4,557 ± 1,402	4,344 ± 1,062	0.12	4,549 ± 1,405	0.35
Type-IIA fibers/total fibers	0.34 ± 0.10	0.35 ± 0.14	0.62	0.25 ± 0.10	<0.01
Type-IIA fiber CSA (μm2)	5,875 ± 1,613	4,769 ± 1,278	0.03	5,148 ± 1,795	0.36
Type-2IIA/X fibers/total fibers	0.21 ± 0.07	0.17 ± 0.08	0.12	0.34 ± 0.16	<0.01
Type-IIA/X fiber CSA (μm2)	5,056 ± 1,186	4,493 ± 1,136	0.33	4,437 ± 1,574	0.91
Extracellular matrix/CSA	0.10 ± 0.03	0.16 ± 0.05	<0.01	0.15 ± 0.04	0.42
Satellite cells/fiber	0.17 ± 0.05	0.10 ± 0.04	<0.01	0.11 ± 0.04	0.18

^*The values are given as the mean and standard deviation.

^†Injured limb after surgery compared with before surgery.