Table 4.

Multiple linear regression analysis for association of rs4646994 (angiotensin-converting-enzyme insertion/deletion) with carotid atherosclerosis progression in patients with type 2 diabetes mellitus.

Parameters	∆ CIMT/Year		∆ Number of Segments		∆ Sum of Plaque Thickness
	β	p Value	β	p Value	β	p Value
A) rs4646994
Hypertension (yes/no)	0.144	0.59	0.206	0.88	0.272	0.53
Systolic blood pressure	0.031	0.42	0.027	0.15	0.014	0.69
ID	0.141	0.49	0.116	0.51	0.845	0.26
DD	0.102	0.63	0.146	0.41	0.952	0.04

All models were adjusted to age, sex, smoking habits, serum levels of Hb A_1c, statin treatment and initial values of the dependent variables. Reference groups are homozygotes for the I allele.