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. 2016 Aug 2;19(1):63–70. doi: 10.1515/bjmg-2016-0008

Table 5.

Relationship of the PECAM gene polymorphism 373 C/G (rs668) genotypes to the presence of plaques/ unstable plaques of the carotid arteries in patients with type 2 diabetes mellitus at the beginning of the study.

Presence of Plaques Presence of Unstable Plaques
Parameters OR (95% CI) p Value OR (95% CI) p Value
Hypertension (0 = no; 1 = yes) 1.88 0.35 1.38 0.52
Systolic pressure (mm Hg) 0.24 0.68 0.26 0.32
Serum LDL (mmol/L) 1.41 0.41 1.34 0.25
Serum HDL (mmol/L) 0.11 0.02 0.31 0.34
Hb A1c (%) 0.89 0.03 1.23 0.43
CG allele 1.03 0.49 0.72 0.17
GG allele 1.18 0.03 0.68 0.51

OR (95% CI): odds ratio (95% confidence interval); LDL: low-density lipoprotein; HDL: high-density lipoprotien; all models were adjusted by age, sex, smoking habits and treatment with statins. The reference group are homozygotes for the C allele (the CC genotype).