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. Author manuscript; available in PMC: 2017 Feb 4.
Published in final edited form as: N Engl J Med. 2016 Aug 4;375(5):435–442. doi: 10.1056/NEJMoa1516257

Table 3. Risk of Exertional Rhabdomyolysis among Black U.S. Army Soldiers.

Characteristic Hazard Ratio (95% CI) P Value
Sickle cell trait
 Negative Reference
 Positive 1.54 (1.12–2.12) 0.008

Sex
 Male Reference
 Female 0.51 (0.38–0.67) <0.001

Age category
 17–23 yr Reference
 24–28 yr 1.10 (0.80–1.49) 0.56
 29–35 yr 1.27 (0.91–1.77) 0.16
 ≥36 yr 1.57 (1.06–2.32) 0.02

Modified BMI category*
 <25.0 Reference
 25.0–29.9 1.21 (0.95–1.54) 0.13
 ≥30.0 1.39 (1.04–1.86) 0.03

APFT score
 <270 or no score Reference
 ≥270 1.13 (0.87–1.47) 0.37

Tobacco use in previous 6 mo
 No Reference
 Yes 1.54 (1.23–1.94) <0.001

Statin prescription in previous 2 mo
 No Reference
 Yes 2.89 (1.51–5.55) 0.001

Antipsychotic-agent prescription in previous 2 mo
 No Reference
 Yes 3.02 (1.34–6.82) 0.008

Stimulant prescription in previous 2 mo
 No Reference
 Yes 1.63 (0.41–6.59) 0.49
*

Modified BMI indicates that all participants with a BMI of 25 or less (normal and underweight) were included with those with unknown BMI to create the reference category.