Table 2. Baseline characteristics of adolescents infected with S. mansoni stratified by treatment group.
The study was carried out in the villages of Bigouin and Biakalé in western Côte d’Ivoire, between May and June 2015.
| Moxidectin (N = 34) | Synriam plus praziquantel (N = 30) | Synriam (N = 32) | Praziquantel (N = 32) | Total (N = 128) | |
|---|---|---|---|---|---|
| Age (years) | 12.9 (0.2) | 12.7 (0.2) | 12.8 (0.3) | 12.8 (0.3) | 12.8 (0.1) |
| Males N (%) | 17 (50.0) | 22 (73.3) | 15 (46.8) | 17 (53.1) | 71 (55.5) |
| Hemoglobin (g/dl) [mean (SD)] | 12.2 (0.1) | 11.7 (0.2) | 11.7 (0.2) | 11.8 (0.2) | 11.8 (0.1) |
| Weight (kg) [mean (SD)] | 34.4 (1.5) | 32.8 (1.5) | 39.8 (2.2) | 33.97 (1.2) | 35.2 (0.8) |
| Height (cm) [mean (SD)] | 138.5 (2.0) | 136.2 (2.5) | 144.7 (2.1) | 137.8 (1.8) | 139.3 (1.1) |
| EPG AM | 207.5 | 249.8 | 191.7 | 219.8 | 216.6 |
| EPG GM | 100.9 | 103.2 | 99.2 | 139.9 | 109.1 |
| Light intensity N (%) | 17 (50) | 13 (43.3) | 15 (46.8) | 14 (43.8) | 59 (46.1) |
| Moderate intensity N (%) | 13 (38.2) | 11 (36.7) | 13 (40.6) | 12 (37.5) | 49 (38.3) |
| High intensity N (%) | 4 (11.8) | 6 (20.0) | 4 (12.5) | 6 (18.7) | 20 (15.6) |
| CCA N (%) | 29 (90.6) | 27 (90.0) | 26 (86.7) | 29 (90.0) | 111 (89.5) |
| Trace N (%) | 2 (6.3) | 4 (13.3) | 4 (6.7) | 0 (0) | 8 (6.5) |
| Low intensity N (%) | 5 (15.6) | 2 (6.7) | 4 (13.3) | 3 (3.4) | 14 (11.3) |
| High intensity N (%) | 22 (68.8) | 21 (70) | 20 (66.7) | 26 (81.3) | 89 (71.8) |
| STH coinfection N (%) | 12 (35.3) | 16 (53.3) | 13 (40.6) | 8 (25.0) | 49 (38.3) |
| Malaria RDT positive N (%) | 24 (70.6) | 24 (80) | 26 (81.2) | 25 (78.1) | 99 (77.3) |
| Malaria direct smear positive N (%) | 28 (82.3) | 22 (73.3) | 24 (75) | 27 (84.4) | 101 (78.1) |
SD, standard deviation; AM, arithmetic mean; GM, geometric mean, EPG, eggs per gram, RDT, rapid diagnostic test