Table 3. Cis-eQTL and genetic associations with E/e′ within the IL18 and FUCA2 gene regions.
SNP | Gene | SCD eQTL | Lateral E/e′ | GTEx eQTL | |||
---|---|---|---|---|---|---|---|
β | P | β | P | β | P | ||
rs11214107 | IL18 | 0.368 | 0.045 | 4.343 | 0.030 | 0.10 | 0.43 |
rs9496646 | FUCA2 | 0.301 | 0.001 | 2.626 | 0.003 | -0.12 | 0.015 |
rs8161 | FUCA2 | -0.240 | 0.007 | -1.589 | 0.076 | -0.12 | 0.015 |
rs13197626 | FUCA2 | -0.289 | 0.008 | -0.6028 | 0.58 | 0.096 | 0.051 |
rs6915645 | FUCA2 | 0.276 | 0.036 | 0.4356 | 0.7432 | -0.050 | 0.33 |