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. Author manuscript; available in PMC: 2016 Sep 16.
Published in final edited form as: Biochem J. 2009 Apr 15;419(2):369–375. doi: 10.1042/BJ20082270

Figure 3. The function of the CIC presequence is independent of chaperone binding.

Figure 3

(A) pCIC and mCIC were radiolabelled and separated by centrifugation as stated in the legend to Figure 2(A). The supernatants (S) and pellets (P) were analysed. Results are means ± S.D. (n ≥3). (B) The binding of radiolabelled pCIC and mCIC to TPR1 and TPR2A was assayed as stated in the legend to Figure 2(B). Results are means ± S.D. (n ≥3). (C and D) The mitochondrial import of radiolabelled pCIC and mCIC was assayed as stated in the legend to Figure 2(C) in the presence (○) or absence (●) of the C-Bag (C) or C-90 (D) fragments.