Figure 4:
Treatment schematic for IgG4-related disease. *As diagnosed by international consensus guidance.43 †Consider B-cell depletion if the patient is resistant to or intolerant of glucocorticoids and therapies available to the clinician. ‡Other agents include calcineurin inhibitors, cyclophosphamide, mycophenolate mofetil and methotrexate. B-cell depletion could be considered. §Predictors of relapse in IgG4-related sclerosing cholangitis or autoimmune pancreatitis include coexisting diabetes, or a high burden of biliary involvement. Note: IgG4-RD = IgG4-related disease.