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Docking into human IGF-1R and EGFR catalytic domains in the inhibited conformation.
| Score IGF-1R | Score EGFR | |
|---|---|---|
| 1,3-disubstituted-8-amino-imidazopyrazine derivative | − 58.13 | - |
| 4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones | - | − 54.75 |
| Gallic acid (GA) | − 27.50 | nd* |
| Ellagic acid (EA) | − 34.00 | − 21.87 |
nd- not docked favorably
