Skip to main content
. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: J Mol Cell Cardiol. 2016 Jul 1;98:1–10. doi: 10.1016/j.yjmcc.2016.06.067

Figure 2. Vitamin D deficiency eliminates anti-contractile effects of PVAT in mesenteric resistance arteries.

Figure 2

Isometric tension was measured on second order mesenteric arteries from mice maintained on vitamin D-deficient diet (D def; squares), vitamin D-sufficient diet (D suff; circles) or vitamin D-supplemented diet (D supp; triangles). The mesenteric artery rings were either dissected free of PVAT (open symbols) or had the PVAT remaining intact (filled symbols). Dose-dependent contraction was assessed in response to 5-HT (A), angiotensin II (Ang II) (B), endothelin-1 (ET-1) (C), PE (D) or KCl (E). Data represent means ± SE (n=5 mice). *p<0.05 PVAT vs. no PVAT. #p<0.05 D def or D supp vs. D suff.