Table 1.

Total Turnover Numbers (TTNs) for Selected Enzymatic Reactions^a

Catalytic system	Substrate
	5	8	9	10	11	12
MycCI/MycCIIb	6.8 ± 0.4	65 ± 1	85 ± 2	72 ± 1	87 ± 4	89 ± 2
MycCI-RhFRED	0.6 ± 0.1	18.8 ± 0.8	167 ± 13	49.3 ± 0.7	177 ± 7	114 ± 4
TylHI/TylHIIb	0	0	0	0	1.0 ± 0.2	18.2 ± 0.8
TylHI/MycCIIb	0	0	0	0	0.2 ± 0.1	69 ± 2
TylHI-RhFRED	0	0	0	0	0.8 ± 0.1	162 ± 6
MycCIS172A/MycCII b	2.0 ± 0.1	74 ± 3	71 ± 2	77 ± 1	61 ± 4	66 ± 4

^aTTN = mol product/mol P450. Reported errors are standard deviations calculated from experiments performed in triplicate.

^bIncludes MBP-FdR.