. 2016 Oct;59(4 Suppl):S29–S39. doi: 10.1016/j.jadohealth.2016.06.022

Table 2.

Summary of findings for the effect of micronutrient supplementation

Quality assessment						Summary of findings
Number of studies	Design	Limitations	Consistency	Directness		Number of participants		RR (95% CI)
Number of studies	Design	Limitations	Consistency	Generalizability to population of interest	Generalizability to intervention of interest	Intervention	Control	RR (95% CI)
Anemia: moderate^a outcome specific quality of evidence
11	RCT/quasi	Eight studies had unclear allocation concealment and sequence generation	Two studies showed significant improvement Considerable heterogeneity, I² = 72%	All interventions targeted adolescents from both developing and developed countries. Most of the studies involved females only	Majority of the studies involved diet, exercise and behavior change for lifestyle modification, and micronutrient supplementation	6,350	5,511	.69 (.62–.76); (I²: 72%)

CI = confidence interval; RCT = randomized controlled trial; RR = relative risk.

Downgraded for study design and heterogeneity.