Oxysterol profile in the liver of rats fed high-fat (HFA), high-cholesterol (HCh) and high-fat+high−cholesterol (HFA+HCh) diet for 6 weeks. Data are expressed as mean ± SDM of the percentage relative to the levels of rats fed the standard chow (CTRL). Statistical differences were assessed by the student's t-test. 7α-OHC, 7α-hydroxycholesterol; 7β-OHC, 7β-hydroxycholesterol; 27-OHC, 27-hydroxycholesterol; 25-OHC, 25-hydroxycholesterol; 4β-OHC, 4β-hydroxycholesterol; 5α,6α-epoxy, 5α,6α-epoxycholesterol; 5β,6β-epoxy, 5β,6β-epoxycholesterol; triol, 5α-cholestane-3β,5,6β-triol; 7-KC, 7-ketocholesterol; 6-oxo, 6-oxo-cholestan-3β,5α-diol.