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. 2016 Sep 14;20(3):392–405. doi: 10.1016/j.chom.2016.08.005

Figure 3.

Figure 3

Putatively Indirect and Direct Effects of ISGs on Incoming HIV-1 and HIV-2 Infection

(A) Activation of integrated IFNβ promoter driven luciferase reporter genes in HEK293T and THP-1 cells following transduction with lentiviral vectors encoding macaque and human ISGs.

(B) Activation of integrated ISRE-driven GFP reporter gene in HEK293T cells following transduction with lentiviral vectors encoding macaque and human ISGs.

(C and D) Infectious titers of HIV-1-GFP and HIV-2-GFP in MT4 cells (C) and THP-1 cells (D) transduced with SCRPSY vectors expressing selected ISGs. Titers are mean + SD.