Fig. 4.

Effects of monocrotaline-induced pulmonary hypertension on expression of metabolic markers in rat right ventricle. Expression levels of glyceraldehyde 3-phosphate dehydrogenase (GAPDH), peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α), succinate dehydrogenase (SDH), cytochrome c oxidase (COX) 4, and COX1 are shown relative to 18S (a), as concentration (b) and per nucleus (c). Note that the right axis in a and b only applies to COX1. COX1 expression levels per nucleus are not presented because this subunit is encoded by the mitochondrial DNA. ***p < 0.001, **p < 0.01, *p < 0.05. White bars: control, black bars: PH