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. 2016 Jun 22;41(11):2638–2646. doi: 10.1038/npp.2016.82

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Copyright © 2016 American College of Neuropsychopharmacology

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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Subjective effects of lysergic acid diethylamide (LSD) over time on the Visual Analog Scales (VASs). LSD or placebo was administered at t=0. The data are expressed as mean±SEM in 24 and 16 subjects in the 100 and 200 μg LSD dose groups, respectively. LSD significantly increased ratings on all VASs with significant dose–response effects, except for ratings of ‘happy'. The corresponding maximal effects and statistics are shown in Table 1. Emotion recognition (Face Emotion Recognition Task), empathy (Multifaceted Empathy Test), and social value orientation (SVO) tests were conducted 5–6 and 7–8 h after the administration of the 100 and 200 μg LSD dose, respectively. +/*p<0.05, ++/**p<0.01, +++/***p<0.001 for the 100/200 μg LSD dose, respectively, compared with placebo (T-tests).