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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Anesth Analg. 2016 Nov;123(5):1210–1219. doi: 10.1213/ANE.0000000000001234

Figure 4. Physostigmine decreases BSP during continuous inhalation of 2.0% isoflurane.

Figure 4

(A)-(F) The BSP computed for each of 6 rats during continuous inhalation of 2.0% isoflurane, from 10 minutes before physostigmine (0.2 mg/kg IV) to 20 minutes after physostigmine. All 6 rats had large reductions in BSP after physostigmine administration. When comparing the “pre-drug” and “post-drug” periods shown in the figure (indicated by the horizontal bars), physostigmine induced statistically significant reductions in BSP in 6/6 rats.