Figure 6. Methylphenidate does not induce significant changes in BSP during continuous inhalation of 2.0% isoflurane.
(A)-(F) The BSP computed for each of 6 rats during continuous inhalation of 2.0% isoflurane, from 10 minutes before methylphenidate (5 mg/kg IV) to 20 minutes after methylphenidate administration. When comparing the “pre-drug” and “post-drug” periods shown in the figure (indicated by the horizontal bars), methylphenidate did not induce statistically significant changes in BSP in any of the rats.