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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Schizophr Res. 2016 Jun 16;176(2-3):320–326. doi: 10.1016/j.schres.2016.06.011

Table 1. Comparison of Study Participants With and Without Schizophrenia.

Healthy Comparison (HC) Schizophrenia t df p Cohen's d
N Mean Std Dev N Mean Std Dev
Sociodemographic Factors
Age (years) 120 48.6 11.6 134 48.1 10.1 0.34 237.4 0.731 0.044
Gender (% women) 54% 45% 2.23* 1 0.167 1.49**
Education (years) 120 14.5 2.2 134 12.4 2.0 8.00 243.4 <0.001
Current packs of cigarettes per day 120 0.02 0.08 134 0.38 0.48 -8.5 142.4 <0.001 -1.04
Number of years smoked 120 5.4 10.6 133 16.3 14.7 -6.83 239.2 <0.001 -0.84
Substance Abuse (Yes) 19 15% 55 41% 19.85* 1 <0.001 4.45**
Clinical Factors
Duration of illness (years) 133 25.1 11.2
Antipsychotic dose*** 134 1.8 1.5
PHQ-9 Score 116 2.0 2.9 130 7.6 6.6 -8.72 182.0 <0.001 -1.29
Positive symptoms 119 0.3 0.7 134 6.5 4.3 -16.63 141.4 <0.001 -2.80
Negative symptoms 118 1.4 2.3 134 7.4 4.4 -13.93 203.6 <0.001 -1.95
SF-36 Mental Composite score 117 54.6 5.8 132 43.4 11.3 9.97 201.7 <0.001 1.40
Executive function 120 0.4 0.6 134 -0.5 0.7 11.63 249.9 <0.001 1.47
Physical Factors
SF-36 Physical Composite Score 117 51.5 8.8 132 43.2 10.1 6.99 247.0 <0.001 0.89
CIRS Total score 101 3.2 3.2 116 6.8 4.9 -6.45 200.3 <0.001 -0.91
BMI (kg/m2) 117 27.7 7.0 132 32.2 7.4 -4.90 245.7 <0.001 -0.63
hs-CRP (mg/L) 116 2.18 3.5 131 5.08 8.8 -3.47 174.7 0.001 -0.53
Plasma F2-isoprostanes (ng/mL) 120 0.032 0.015 134 0.040 0.021 -3.31 243.4 0.001 -0.43
*

X2 value

**

r value

***

Antipsychotic medication daily dosages were converted to WHO average daily doses based on published standards (WHO, 2009, 2010)

Scale for the Assessment of Positive Symptoms (SAPS) total score

††

Scale for the Assessment of Negative Symptoms (SANS) total score

PHQ-9 = patient health questionnaire

SF = Short Form Health Survey

CIRS = Cumulative Illness Rating

BMI = body mass index

hs-CRP = high sensitivity C-reactive protein