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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: J Immunol. 2016 Aug 24;197(7):2909–2917. doi: 10.4049/jimmunol.1600651

FIGURE 6. Lactic acid suppresses IL-33-mediated inflammation in vivo.

FIGURE 6

C57BL/6 mice were first injected subcutaneously with ketoprofen (1mg/kg in PBS) as an analgesic. 30 minutes later, mice were injected with either LA (4mg/kg in 4% (w/v) solution in PBS) or PBS alone. 16 hours later, mice were injected with either PBS or 1μg of IL-33. After 4 hours, mice were euthanized, blood plasma was collected from cardiac puncture, and samples analyzed by ELISA. Results are expressed as mean ±SEM and n=7. *, p<0.05; **, p<0.01; ***, p<0.001; ****, p<0.0001; NS, not significant.