Table 2.
Arm Number (%) | Variable | Value | Number (%) |
---|---|---|---|
Arm 1 18 (26%) | Gender | Male | 8 (44%) |
Female | 10 (56%) | ||
Age (years) | >50 | 3 (17%) | |
≤50 | 15 (83%) | ||
Disease | AML | 11 (61%) | |
MDS | 2 (11%) | ||
CML | 5 (28%) | ||
Disease status at transplantation | CR | 3 (17%) | |
Active disease | 67 (83%) | ||
Cytogenetics | Good | 1(9%) | |
Intermediate | 6(55%) | ||
Poor | 4(36%) | ||
Donor type | MRD | 9 (50%) | |
MUD | 9 (50%) | ||
Mismatched | 0 | ||
Arm 2 7 (10%) | Gender | Male | 6 (86%) |
Female | 1 (14%) | ||
Age (years) | >50 | 5 (71%) | |
≤50 | 2 (29%) | ||
Disease | AML | 4 (57%) | |
MDS | 1 (14%) | ||
CML | 2 (29%) | ||
Disease status at transplantation | CR | 1 (14%) | |
Active disease | 6 (86%) | ||
Cytogenetics | Good | 0 | |
Intermediate | 2(50 %) | ||
Poor | 2(50 %) | ||
Donor type | MRD | 4 (57%) | |
MUD | 3 (43%) | ||
Mismatched | 0 | ||
Arm 329 (41%) | Gender | Male | 15 (52%) |
Female | 14 (48%) | ||
Age (years) | >50 | 10 (34%) | |
≤50 | 19 (66%) | ||
Disease | AML | 23 (79%) | |
MDS | 2 (7%) | ||
CML | 4 (14%) | ||
Disease status at transplantation | CR | 6 (21%) | |
Active disease | 23 (79%) | ||
Cytogenetics | Good | 3(3%) | |
Intermediate | 13(57%) | ||
Poor | 7(30%) | ||
Donor type | MRD | 7 (24%) | |
MUD | 21 (72%) | ||
Mismatched | 1 (4%) | ||
Arm 4 16 (23%) | Gender | Male | 10 (63%) |
Female | 6 (37%) | ||
Age (years) | >50 | 7 (44%) | |
≤50 | 9 (56%) | ||
Disease | AML | 11 (69%) | |
MDS | 3 (19%) | ||
CML | 2 (12%) | ||
Disease status at transplantation | CR | 3 (19%) | |
Active disease | 13 (81%) | ||
Cytogenetics | Good | 2(18%) | |
Intermediate | 6(55%) | ||
Poor | 3(27%) | ||
Donor type | MRD | 7 (44%) | |
MUD | 8 (50%) | ||
Mismatched | 1 (6%) |
Abbreviations: AML, acute myeloid leukemia; myelodysplastic syndrome, MDS; chronic myeloid leukemia, CML; MRD, matched related donor; MUD, matched unrelated donor; CR, complete remission.