Table 4.
Logistic regression models on the subgroup admitted after elective cardiac surgery
| Outcome: 30-day mortalitya (n = 2350) | Outcome: hospital mortalityb (n = 2156) | |||||||
|---|---|---|---|---|---|---|---|---|
| n | % outcome (%) | Odds ratio (95 % CI) versus normochloremia | p value | n | % outcome (%) | Odds ratio (95 % CI) versus normochloremia | p value | |
| Chloride category | ||||||||
| Normochloremia | 287 | 5.6 | 246 | 13.4 | ||||
| Hypochloremia | 21 | 23.8 | 3.49 (0.62–19.62) | 0.16 | 15 | 40.0 | 1.45 (0.30–7.18) | 0.64 |
| Moderate hyperchloremia | 596 | 3.0 | 0.63 (0.26–1.54) | 0.31 | 550 | 5.1 | 0.43 (0.22–0.83) | 0.01 |
| Severe hyperchloremia | 1446 | 2.7 | 0.57 (0.22–1.44) | 0.23 | 1345 | 4.5 | 0.37 (0.18–0.73) | 0.004 |
| n | % outcome (%) | Odds ratio (95 % CI) versus mean SID | p value | n | % outcome (%) | Odds ratio (95 % CI) versus mean SID | p value | |
|---|---|---|---|---|---|---|---|---|
| SIDa category | ||||||||
| Intermediate SIDa | 941 | 2.6 | 873 | 5.2 | ||||
| Low SIDa | 1110 | 2.0 | 1.46 (0.68–3.11) | 0.34 | 1015 | 4.1 | 1.13 (0.63–2.03) | 0.68 |
| High SIDa | 229 | 10.7 | 0.85 (0.39–1.83) | 0.67 | 268 | 14.9 | 0.71 (0.38–1.31) | 0.27 |
| Area under ROC 88.3 % | Area under ROC 83.9 % | |||||||
| Maximal VIF 3.53 | Maximal VIF 3.58 | |||||||
| Tolerance 0.66 | Tolerance 0.66 | |||||||
SIDa apparent strong ion difference (excl. lactate), ROC Receiver under Operating Characteristics Curve, VIF variance inflation factor
aConfounders adjusted for in the model: sodium (high vs. normal, low vs. normal*), SAPS-3, RIFLEcrea, lactate, heart failure*, COPD*, pCO2* (low, normal, high), albumin*, SIG, potentiometry type (*p > 0.05). RIFLEurine omitted because of collinearity
bConfounders adjusted for in the model: sodium (high vs. normal, low vs. normal*), SAPS-3, RIFLEcrea, lactate, heart failure*, COPD, pCO2* (low, normal, high), albumin*, SIG, potentiometry type (*p > 0.05). RIFLEurine omitted because of collinearity