Table 3.
Receiver operating curve analysis using Greek population values for osteoporosis risk
| Area | 95%CI | Cut-off | Sensitivity | Specificity | PPV | NPV | P-value | ||
| SCORE1 | 0.613 | 0.576 | 0.650 | 20.75 > | 61% | 60% | 46% | 73% | < 0.0005 |
| ORAI1 | 0.640 | 0.603 | 0.676 | 9.5 > | 72% | 52% | 46% | 76% | < 0.0005 |
| 10.5 > | 62% | 62% | 48% | 74% | |||||
| ABONE1 | 0.631 | 0.595 | 0.668 | 1.5 > | 65% | 41% | 32% | 85% | < 0.0005 |
| OST1 | 0.643 | 0.607 | 0.678 | -2.9 > | 77% | 46% | 45% | 78% | < 0.0005 |
| BW1 | 0.592 | 0.555 | 0.630 | 70.5 < | 51% | 61% | 42% | 68% | < 0.0005 |
| OSIRIS1 | 0.609 | 0.572 | 0.645 | 0.5 < | 59% | 59% | 44% | 71% | < 0.0005 |
1
High risk for osteoporosis: T-score ≤ -2. SCORE: Simple calculated osteoporosis risk estimation; ORAI: Osteoporosis risk assessment instrument; ABONE: Age, body size, no estrogen; OST: Osteoporosis self-assessment tool; BW: Body weight; OSIRIS: Osteoporosis index of risk; PPV: Positive predictive value; NPV: Negative predictive value.