Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Sep 17;17:738. doi: 10.1186/s12864-016-3075-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 2 — Odds ratios and conditional odds ratios of MI for non-linearly interacting pairs. a Conditional odds ratios of MI from one standard deviation increase in the mean expression of gene A, plotted against expression of the second interacting gene, gene B. Histograms of gene B expression are displayed above each panel. The odds ratio is defined as:odds(Ex_A + sd(Ex_A))/odds(Ex_A) where Ex_A and sd(Ex_A) denote the expression level and the standard deviation of expression of gene A respectively. Red lines indicate an odds ratio of 1. In panel b the interaction is displayed as surface plot, which is a three dimensional plot of expression of the two genes versus the log-odds of MI. The curvature of the saddle shape surface indicates the magnitude of the interaction term in the model