Table 1.
Pig ID |
Human islets |
TX | Surv (week) |
OHS | IIR | FBR | IS | SS | TIR (µm) |
---|---|---|---|---|---|---|---|---|---|
1 | − | PV | 0 | 0 | 0.2 | 0 | 0.4 | 0.6 | 0.00±0.00 |
2 | − | PV | 2 | 2 | 0.6 | 1.6 | 0 | 1 | 22.00±17.15 |
3 | + | PV | 2 | 2.2 | 0.8 | 1.4 | 0.4 | 0.6 | 142.90±59.27 |
4 | − | SC | 2 | 3 | 1.7 | 0.4 | 1 | 0 | 51.30±20.12 |
4 | − | SM | 2 | 2.3 | 0.4 | 0.2 | 1 | 0 | 56.49±25.28 |
4 | − | LS | 2 | 1.8 | 0 | 0 | 0 | 1 | 21.17±11.26 |
4 | − | KS | 2 | 2 | 0 | 0 | 0 | 0.8 | 15.83±10.72 |
5 | − | LS | 2 | 1.3 | 0.3 | 0 | 0 | 1 | 20.83±7.35 |
5 | − | KS | 2 | 2 | 1 | 0.5 | 0.5 | 0.5 | 26.36±18.91 |
6 | − | LS | 2 | 1.3 | 0.3 | 0 | 0 | 1 | 18.92±12.70 |
6 | − | KS | 2 | 2 | 1 | 0.3 | 0.7 | 0.3 | 17.22±10.82 |
7 | + | KS | 2 | 2 | 1 | 1 | 1 | 0 | 192.47±63.26 |
8 | + | LS | 2 | 2 | 0.8 | 0.6 | 1 | 0 | 78.50±37.02 |
8 | + | KS | 2 | 2.4 | 1.4 | 0.4 | 1 | 0 | 151.11±64.20 |
TX=transplantation site, PV=portal vein, SC=subcutaneous, SM=skeletal muscle, LS=liver subcapsular space, KS=kidney subcapsular space, Surv=survival period in weeks, OHS=overall histology score, IIR = Innate immune response, FBR=foreign body reaction, IS=inflammation score, SS=stromal score, TIR=Thickness of immune response