Table A1.
Patient characteristics by WHO classification
| All (n = 1054) | Control (n = 316) | WHO‐group 1 (n = 376) | WHO‐group 2 (n = 143) | WHO‐group 3 (n = 78) | WHO‐group 4 (n = 115) | WHO‐group 5 (n = 26) | |
|---|---|---|---|---|---|---|---|
| Gender (% female) | 66 | 65 | 68 | 76 | 41 | 63 | 65 |
| Age (years) | 60 ± 15 | 58 ± 15 | 57 ± 17 | 66 ± 12 | 65 ± 12 | 64 ± 14 | 59 ± 11 |
| BMI (kg‐m2) | 27 ± 7 | 27 ± 7 | 26 ± 6 | 30 ± 8 | 26 ± 6 | 25 ± 7 | 24 ± 4 |
| BSA (m2) | 1.9 ± 0.3 | 1.9 ± 0.3 | 1.8 ± 0.3 | 2.0 ± 0.3 | 1.9 ± 0.2 | 1.9 ± 0.5 | 1.7 ± 0.2 |
| Heart rate (/min) | 78 ± 15 | 75 ± 13 | 81 ± 15 | 75 ± 15 | 84 ± 16 | 77 ± 14 | 87 ± 17 |
| SaO2 (%) | 94 ± 5 | 96 ± 3 | 93 ± 4 | 94 ± 4 | 89 ± 7 | 93 ± 4 | 90 ± 9 |
| SvO2 (%) | 67 ± 10 | 72 ± 7 | 64 ± 10 | 66 ± 10 | 62 ± 10 | 62 ± 10 | 67 ± 9 |
| mRAP (mmHg) | 7 ± 6 | 5 ± 6 | 8 ± 6 | 11 ± 6 | 6 ± 4 | 9 ± 5 | 6 ± 4 |
| sPAP (mmHg) | 58 ± 26 | 30 ± 9 | 74 ± 21 | 62 ± 21 | 63 ± 19 | 73 ± 21 | 67 ± 18 |
| dPAP (mmHg) | 22 ± 11 | 11 ± 4 | 29 ± 11 | 23 ± 8 | 25 ± 9 | 27 ± 9 | 26 ± 10 |
| mPAP (mmHg) | 36 ± 16 | 19 ± 5 | 46 ± 13 | 38 ± 12 | 40 ± 12 | 44 ± 12 | 41 ± 11 |
| PAWP (mmHg) | 11 ± 5 | 10 ± 5 | 9 ± 4 | 18 ± 6 | 10 ± 4 | 10 ± 3 | 9 ± 4 |
| CI (L/min/m2) | 3.1 ± 1.2 | 3.6 ± 1.3 | 2.8 ± 1.1 | 3.0 ± 1.2 | 3.0 ± 0.9 | 2.5 ± 1.0 | 4.1 ± 1.3 |
| PVR (Wood units) | 5.5 ± 4.9 | 1.5 ± 0.9 | 8.5 ± 5.1 | 3.9 ± 3.0 | 6.2 ± 4.3 | 8.3 ± 4.9 | 5.2 ± 2.8 |
| TPG (mmHg) | 25 ± 16 | 9 ± 5 | 36 ± 14 | 20 ± 10 | 30 ± 12 | 34 ± 12 | 32 ± 11 |
| DPG (mmHg) | 11 ± 12 | 1 ± 4 | 19 ± 11 | 5 ± 8 | 15 ± 9 | 17 ± 8 | 16 ± 9 |
BMI, body mass index; BSA, body surface area; SaO2, arterial oxygen saturation; SvO2, venous oxygen saturation; mRAP. mean right atrial pressure; sPAP, dPAP and mPAP, systolic, diastolic and mean pulmonary arterial pressure; CI, cardiac index; PVR, pulmonary vascular resistance; TPG and DPG, transpulmonary and diastolic pressure gradient. Average ± SD.