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. 2016 Sep 19;6:33694. doi: 10.1038/srep33694

Figure 1. Schematic diagram for BDNF detection system using IMEs.

Figure 1

(a) IMEs of 4 pairs on a chip with a PDMS microfluidic chip for the minimization of microdialysis sample volume consumption. (b) Scanning electron microscope image of an IME. (c) Illustration of impedance change elicited by the interaction of BDNF with the anti-BDNF antibody. (d) BDNF detection and quantification during measurement from the PDMS microfluidic channel. (e) Simplified equivalent circuit of the IME for BDNF detection at 100 Hz before the interaction of BDNF with the anti-BDNF antibody and (f) after the interaction of BDNF with the anti-BDNF antibody.