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(A) T1-weighted MRI of a large poorly differentiated tumor bearing prostate after GSCE with Gd-CP027. Rectangle shows dorsal lobe with minimal signal enhancement. (B) H&E stain showing dorsal lobe with identified high-grade PIN areas at 20× and 40× . (C) PCNA stain of same region as in H&E showing positive PCNA indicative of malignant transformation at 20× and 40×.
