Table S1.
Cross | Offspring genotype | No. of males | Cryptorchism | Atrophy | Miscellaneous | Total TAs | ||||
No. | Frequency, % | No. | Frequency, % | No. | Frequency, % | No. | Frequency, % | |||
129/Sv control strain | ||||||||||
129/Sv × 129/Sv | 361 | 26 | 7.2 | 39 | 10.8 | 1 | 0.3 | 66 | 18.3 | |
A1cfKO/+ test crosses | ||||||||||
A1cfKO/+ × 129/Sv | Wild-type | 126 | 6 | 4.8 | 6 | 4.8 | 1 | 0.8 | 13 | 10.3 |
A1cfKO/+ | 138 | 10 | 7.2 | 9 | 6.5 | 1 | 0.7 | 20 | 14.5 | |
129/Sv × A1cfKO/+ | Wild-type | 107 | 13 | 12.1 | 3 | 2.8 | 1 | 0.9 | 17 | 15.9 |
A1cfKO/+ | 136 | 8 | 5.9 | 4 | 2.9 | 1 | 0.7 | 13 | 9.6 | |
A1cfKO/+ × A1cfKO/+ | Wild-type | 41 | 2 | 4.9 | 3 | 7.3 | 0 | 0.0 | 5 | 12.2 |
A1cfKO/+ | 107 | 6 | 5.6 | 6 | 5.6 | 0 | 0.0 | 12 | 11.2 | |
Ago2KO/+ test crosses | ||||||||||
Ago2KO/+ × 129/Sv | Wild-type | 115 | 12 | 10.4 | 8 | 7.0 | 0 | 0.0 | 20 | 17.4 |
Ago2KO/+ | 91 | 4 | 4.4 | 13 | 14.3 | 0 | 0.0 | 17 | 18.7 | |
129/Sv × Ago2KO/+ | Wild-type | 144 | 10 | 6.9 | 16 | 11.1 | 2 | 1.4 | 27 | 18.8 |
Ago2KO/+ | 153 | 12 | 7.8 | 17 | 11.1 | 1 | 0.7 | 30 | 19.6 | |
Ago2KO/+ × Ago2KO/+ | Wild-type | 37 | 7 | 18.9 | 2 | 5.4 | 0 | 0.0 | 9 | 24.3 |
Ago2KO/+ | 33 | 6 | 18.2 | 5 | 15.2 | 0 | 0.0 | 11 | 33.3 |