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. 2016 Aug 31;113(37):E5425–E5433. doi: 10.1073/pnas.1604773113

Table S1.

Occurrence of males with cryptorchism, atrophy, and other TAs in 129/Sv control cross and in A1cfKO/+ and Ago2KO/+ reciprocal backcrosses and intercrosses

Cross Offspring genotype No. of males Cryptorchism Atrophy Miscellaneous Total TAs
No. Frequency, % No. Frequency, % No. Frequency, % No. Frequency, %
129/Sv control strain
 129/Sv × 129/Sv 361 26 7.2 39 10.8 1 0.3 66 18.3
A1cfKO/+ test crosses
A1cfKO/+ × 129/Sv Wild-type 126 6 4.8 6 4.8 1 0.8 13 10.3
A1cfKO/+ 138 10 7.2 9 6.5 1 0.7 20 14.5
 129/Sv × A1cfKO/+ Wild-type 107 13 12.1 3 2.8 1 0.9 17 15.9
A1cfKO/+ 136 8 5.9 4 2.9 1 0.7 13 9.6
A1cfKO/+ × A1cfKO/+ Wild-type 41 2 4.9 3 7.3 0 0.0 5 12.2
A1cfKO/+ 107 6 5.6 6 5.6 0 0.0 12 11.2
Ago2KO/+ test crosses
Ago2KO/+ × 129/Sv Wild-type 115 12 10.4 8 7.0 0 0.0 20 17.4
Ago2KO/+ 91 4 4.4 13 14.3 0 0.0 17 18.7
 129/Sv × Ago2KO/+ Wild-type 144 10 6.9 16 11.1 2 1.4 27 18.8
Ago2KO/+ 153 12 7.8 17 11.1 1 0.7 30 19.6
Ago2KO/+ × Ago2KO/+ Wild-type 37 7 18.9 2 5.4 0 0.0 9 24.3
Ago2KO/+ 33 6 18.2 5 15.2 0 0.0 11 33.3