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. 2016 Aug 31;113(37):E5425–E5433. doi: 10.1073/pnas.1604773113

Table S5.

Laterality for cryptorchid testes, atrophic testes, and TGCTs in 129/Sv controls and A1cfKO/+ and Ago2KO/+ heterozygous and wild-type sibling males of reciprocal backcrosses and intercrosses

Crosses Offspring Genotype Cryptorchism Atrophy TGCTs
No. unilateral % left No. left No. bilateral No. unilateral % left No. left No. bilateral No. unilateral % left No. left No. bilateral
129/Sv control strain
 129/Sv × 129/Sv Wild-type 26 24 92 0 37 37 100 1 24 15 63 1
A1cfKO/+ test crosses
A1cfKO/+ × 129/Sv Wild-type 6 5 83 0 6 5 83 0 1 0 0 0
A1cfKO/+ 10 10 100 0 9 9 100 0 5 4 80 0
 129/Sv × A1cfKO/+ Wild-type 13 13 100 0 3 3 100 0 5 5 100 0
A1cfKO/+ 8 6 75 0 4 4 100 0 2 1 50 1
A1cfKO/+ × A1cfKO/+ Wild-type 2 2 100 0 3 3 100 0 0 0 ND 1
A1cfKO/+ 6 6 100 0 4 4 100 1 5 3 60 0
Ago2KO/+ test crosses
Ago2KO/+ × 129/Sv Wild-type 12 11 92 0 8 8 100 0 5 4 80 0
Ago2KO/+ 4 4 100 0 13 13 100 0 1 0 0 0
 129/Sv × Ago2KO/+ Wild-type 10 10 100 0 14 13 93 1 6 5 83 0
Ago2KO/+ 12 10 83 0 17 17 100 0 4 2 50 0
Ago2KO/+ × Ago2KO/+ Wild-type 7 6 86 0 2 2 100 0 2 1 50 0
Ago2KO/+ 6 5 83 0 5 4 80 0 2 2 100 0