Table S5.
Crosses | Offspring | Genotype | Cryptorchism | Atrophy | TGCTs | |||||||||
No. unilateral | % left | No. left | No. bilateral | No. unilateral | % left | No. left | No. bilateral | No. unilateral | % left | No. left | No. bilateral | |||
129/Sv control strain | ||||||||||||||
129/Sv × 129/Sv | Wild-type | 26 | 24 | 92 | 0 | 37 | 37 | 100 | 1 | 24 | 15 | 63 | 1 | |
A1cfKO/+ test crosses | ||||||||||||||
A1cfKO/+ × 129/Sv | Wild-type | 6 | 5 | 83 | 0 | 6 | 5 | 83 | 0 | 1 | 0 | 0 | 0 | |
A1cfKO/+ | 10 | 10 | 100 | 0 | 9 | 9 | 100 | 0 | 5 | 4 | 80 | 0 | ||
129/Sv × A1cfKO/+ | Wild-type | 13 | 13 | 100 | 0 | 3 | 3 | 100 | 0 | 5 | 5 | 100 | 0 | |
A1cfKO/+ | 8 | 6 | 75 | 0 | 4 | 4 | 100 | 0 | 2 | 1 | 50 | 1 | ||
A1cfKO/+ × A1cfKO/+ | Wild-type | 2 | 2 | 100 | 0 | 3 | 3 | 100 | 0 | 0 | 0 | ND | 1 | |
A1cfKO/+ | 6 | 6 | 100 | 0 | 4 | 4 | 100 | 1 | 5 | 3 | 60 | 0 | ||
Ago2KO/+ test crosses | ||||||||||||||
Ago2KO/+ × 129/Sv | Wild-type | 12 | 11 | 92 | 0 | 8 | 8 | 100 | 0 | 5 | 4 | 80 | 0 | |
Ago2KO/+ | 4 | 4 | 100 | 0 | 13 | 13 | 100 | 0 | 1 | 0 | 0 | 0 | ||
129/Sv × Ago2KO/+ | Wild-type | 10 | 10 | 100 | 0 | 14 | 13 | 93 | 1 | 6 | 5 | 83 | 0 | |
Ago2KO/+ | 12 | 10 | 83 | 0 | 17 | 17 | 100 | 0 | 4 | 2 | 50 | 0 | ||
Ago2KO/+ × Ago2KO/+ | Wild-type | 7 | 6 | 86 | 0 | 2 | 2 | 100 | 0 | 2 | 1 | 50 | 0 | |
Ago2KO/+ | 6 | 5 | 83 | 0 | 5 | 4 | 80 | 0 | 2 | 2 | 100 | 0 |