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. 2016 Jun 1;44(16):7691–7699. doi: 10.1093/nar/gkw488

Figure 3.

Figure 3.

DNA Damage tolerance of typical replication blocking lesions in partially recombination defective strains: partition between TLS and damage avoidance (DA): (A) major UV lesions, TT-CPD and TT(6-4) and (B) G-AAF. Tolerance events (%) are determined as the efficiency of site-specific integration of a single lesion-containing construct relative to the same amount of damage-free control construct. DA and TLS events are determined as specified in Materials and Methods. DDT profiles in ΔrecA strain were published previously in (6) and found to be mainly due to bacteria that could divide and proliferate following replication of the non-damaged chromatid only (1). Tolerance events for G-AAF in wt was previously published in (7). The data represent the average value and standard deviation of at least 3 independent experiments. T-test was performed to compare values from the different mutants to the recA(wt) strain. For TLS0: *P < 0.05; **P < 0.005. For TLS-2: +P < 0.05; ++P < 0.005; for DA: •P < 0.05; ••P < 0.005.