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. 2016 Sep 19;6:33505. doi: 10.1038/srep33505

Figure 1. Occurrence of mutant EGFR cfDNA in response to therapy.

Figure 1

X-axis time frames, related to the start of TKI therapy (dashed vertical lines). Information about individual treatment schedules (chemo=chemotherapy; TKI-therapy; radiotherapy) are given below the x-axis. Y-axis: numbers of mutant alleles in plasma samples (copies/ml plasma), with sensitizing EGFR mutations labeled with black dots and T790M with grey triangles. White background: oncological stable state; grey background: disease progression.