Table 2.

Analysis of distance traveled (from Figure 5) and number of rearing events (plots not shown) after a 1.68 mg/kg METH challenge dose in vehicle- and mAb7F9-mAb4G9-treated rats in the Phase 2 studies. This table shows the analysis of the total distance traveled data from 0–240 min after METH dosing as well as the analysis of the sequential 1 hr interval data over the 4 hrs of measurement.

Distance traveled (in meters ± SD)
	0–240 min (Total)		0–60 min		60–120 min		120–180 min		180–240 min
Day	Vehicle	mAb	Vehicle	mAb	Vehicle	mAb	Vehicle	mAb	Vehicle	mAb
24	586 ± 202	650 ± 235	117 ± 67	130 ± 46	88 ± 62	199 ± 68a	190 ± 58	207 ± 84	191 ± 81	116 ± 73
28	526 ± 212	585 ± 183	77 ± 50	100 ± 33	48 ± 30	124 ± 30 a	204 ± 88	220 ± 81	197 ± 82	140 ± 77
Number of rearing events (± SD)
24	552 ± 269	852 ± 301	158 ± 139	317 ± 84	97 ± 87	222 ± 86b	143 ± 59	183 ± 90	154 ± 57	130 ± 77
28	509 ± 208	755 ± 288	98 ± 93	189 ±77	51 ± 42	160 ± 91b	176 ± 78	236 ± 81	184 ± 71	170 ± 93

^aStatistical significance compared to time-matched vehicle controls (P < 0.05)

^bP = 0.06.