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. 2016 May 16;12(9):2269–2277. doi: 10.1080/21645515.2016.1182275

Table 1.

Cost-effectiveness of quadrivalent influenza vaccination (QIV) compared to trivalent vaccine (TIV): base case scenario with lifetime horizon.

  TIV QIV Difference
Spanish Healthcare System costs 11,901,394,637 € 12,348,949,428 € 447,554,791 €
Societal costs 34,462,064,137 € 34,364,483,970 € − 97,580,167 €
Total costs 46,363,458,774 € 46,713,433,398 € 349,974,624 €
Life years 1,143,182,206 1,143,233,538 51,332
QALYs
1,038,585,055
1,038,625,059
40,005
ICER (€/QALY) NHS perspective 11,188 €    
ICER (€/QALY) Societal perspective 8,748 €    

TIV: Trivalent influenza vaccine; QIV: Quadrivalent influenza vaccine; QALY: Quality-adjusted life year; ICER: Incremental cost-effectiveness ratio; NHS: National Health System.