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. Author manuscript; available in PMC: 2016 Sep 19.
Published in final edited form as: Histopathology. 2016 Jan;68(1):5–21. doi: 10.1111/his.12876

Figure 4.

Figure 4

Malignant phyllodes tumour with metastasis to the lung. (A) Low magnification of the primary breast phyllodes tumour with a cystic space into which stromal fronds projected. Part of the tumour showed a fibroadenoma-like appearance, whereas the remaining parts were more cellular. (B) Higher magnification of the cellular stromal areas showed sheets of plump spindled cells with enlarged vesicular nuclei with distinct nucleoli and scattered mitoses. Several osteoclastic giant cells were dispersed among the spindled cells. (C) Metastasis to the lung 1 year later showed a similar abnormal spindled population with scattered osteoclastic giant cells. No epithelial component was present in the metastasis.