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. Author manuscript; available in PMC: 2016 Sep 19.
Published in final edited form as: Ann N Y Acad Sci. 2011 May;1225(Suppl 1):E171–E181. doi: 10.1111/j.1749-6632.2011.06000.x

Figure 2.

Figure 2

Image Processing. A 40 μm-thick representative coronal histological section stained for myelin (Panel 1) and a matching 165 μm thick corresponding T1-weighted MRI section from a 3D image (Panel 2). The density of myelination is generally highest in a middle depth of the cortex (around Layer VI); thus, we define our surface at this depth (Panel 3). The 3D surface over the entire cortex at a middle depth is shown using surface rendering (Panel 4). The final step in our processing is to project the local MRI image intensity onto this surface to make a map.