Figure 1. The supernumerary subunits of mammalian complex I.
a) Overview of the complex with the 14 core subunits in blue (FeS clusters in yellow/orange), the 31 supernumerary subunits in red, and the cryoEM density in grey. b-c) Arrangement and structures of the supernumerary subunits around the core membrane (b) and hydrophilic (c) subunits. The core subunits are in surface representation and the supernumerary subunits in cartoon; icons show viewpoints and locations in the complex. Subunits in brackets are behind the domain. The assignments of B12 and AGGG may be reversed. See ED Tables 1 and 2 for the subunit nomenclatures in other species.