Table II.
Odds ratio (OR) for cases of endometriomas and deep infiltrating endometriosis (DIE) versus controls according to tertiles of AGD measures, taking the third tertile as a reference or divided by the median (for DIE).
| All endometriosis (n = 114) versus controls (n = 105) |
||||||||
|---|---|---|---|---|---|---|---|---|
| AGD in tertiles (median for each tertile) | Cases | Controls | Odds ratioa (95% CI) | P-trend | Odds ratiob (95% CI) | P-trend | Odds ratioc (95% CI) | P-trend |
| AGDAF | ||||||||
| 3rd (31.1 mm) | 26 | 48 | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) | |||
| 2nd (24.8 mm) | 34 | 38 | 1.7 (0.9–3.2) | 2.3 (1.1–5.2) | 1.8 (0.71–4.4) | |||
| 1st (19.7 mm) | 54 | 19 | 5.2 (2.6–10.7) | <0.001 | 6.7 (2.6–16.9) | <0.001 | 7.6 (2.8–21.0) | <0.001 |
| AGDAC | ||||||||
| 3rd (86.1 mm) | 37 | 36 | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) | |||
| 2nd (73.6 mm) | 36 | 37 | 0.95 (0.50–1.8) | 1.3 (0.57–2.9) | 1.9 (0.75–4.6) | |||
| 1st (63.3 mm) | 41 | 32 | 1.2 (0.65–2.4) | 0.68 | 1.8 (0.77–4.0) | 0.40 | 2.1 (0.82–5.2) | 0.26 |
| Endometriomas (n = 82) versus controls (n = 105) |
||||||||
| AGD in tertiles (median for each tertile) | Cases | Controls | Odds ratioa (95% CI) | P-trend | Odds ratiob (95% CI) | P-trend | Odds ratioc (95% CI) | P-trend |
| AGDAF | ||||||||
| 3rd (31.8 mm) | 21 | 43 | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) | |||
| 2nd (25.5 mm) | 26 | 35 | 1.5 (0.74–3.2) | 2.1 (0.87–5.1) | 1.7 (0.64–4.4) | |||
| 1st (21.1 mm) | 35 | 27 | 2.7 (1.3–5.5) | 0.03 | 3.7 (1.5–9.3) | 0.02 | 3.5 (1.3–9.4) | 0.04 |
| AGDAC | ||||||||
| 3rd (86.6 mm) | 27 | 35 | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) | |||
| 2nd (74.3 mm) | 27 | 36 | 0.97 (0.48–1.9) | 1.6 (0.69–3.8) | 2.0 (0.76–5.1) | |||
| 1st (65.1 mm) | 28 | 34 | 1.1 (0.53–2.2) | 0.97 | 2.1 (0.88–5.2) | 0.24 | 2.6 (0.96–7.2) | 0.16 |
| DIE (n = 32) versus controls (n = 105) |
||||||||
| AGD divided by median (median for each group) | Cases | Controls | Odds ratioa (95% CI) | P-value | Odds ratiob (95% CI) | P-value | Odds ratioc (95% CI) | P-value |
| AGDAF | ||||||||
| 2nd (30.1 mm) | 3 | 65 | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) | |||
| 1st (20.6 mm) | 29 | 40 | 15.7 (4.5–54.9) | <0.001 | 24.4 (4.1–146) | <0.001 | 41.6 (3.9–438) | 0.002 |
| AGDAC | ||||||||
| 2nd (81.2 mm) | 12 | 56 | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) | |||
| 1st (67.5 mm) | 20 | 49 | 1.9 (0.85–4.3) | 0.12 | 2.9 (0.85–10.4) | 0.09 | 2.6 (0.69–9.4) | 0.15 |
AGDAF: Anogenital distance from the upper verge of the anus to the posterior fourchette.
AGDAC: Anogenital distance from the upper verge of the anus to the anterior clitoral surface.
aUnadjusted OR.
bOR adjusted by age and BMI.
cOR adjusted by age, BMI, vaginal delivery and episiotomy.