Figure 5.

Anti-GBM GN and 5/6 Nx models. (a, b) Representative histology for hematoxylin and eosin-stained, or periodic acid-Schiff-stained sections exhibiting glomerulosclerosis and tubular interstitial injuries in anti-GBM GN (a) and 5/6Nx (b) rats. Scale bar is shown in each photo. (c, d) uNCR, rNRNA, uPCR, and Ccr were compared between normal (empty bar) and disease (black bar) groups for anti-GBM GN rat (c) and 5/6 Nx rat (d). Values are mean ± S.E.M per group. ^#p < 0.05, ^##p < 0.01, ^####p < 0.0001 (unpaired t test). (A color version of this figure is available in the online journal.)