Table 1. The burden of dengue fever, highlighting the number of locally acquired cases in Queensland (Australia), Florida (US), Singapore, and Taiwan.
Years, location | Serotype(s)* | N dengue cases | N locally acquired cases | N hospitalizations (%) | Incidence per 100,000 | N DHF (%) | N deaths (Case Fatality Rate %) | Ref | |
---|---|---|---|---|---|---|---|---|---|
Queensland, Australia | 1996–1997, the Torres Strait | DENV-2 | 208 | 202 | 7 (3.48) | 6.49 | 0 | 0 | [22,23] |
1997–1999, Cairns; Port Douglas; Mossman | DENV-3 | 498 | 493 | 101 (20.28) | 14.86 | 6 (1.20) | 0 | [24–26] | |
2000, Cairns | DENV-2 | 85 | 50 | 0 | 2.44 | 0 | 0 | [25,27] | |
2001, Townsville | DENV-2 | 42 | 8 | 1 (11.11) | 1.17 | 4 (9.52) | 0 | [27] | |
2002, Kuranda; Townsville; Cairns | DENV-2; -1; -4 | 81 | 25 | 0 | 2.22 | 0 | 0 | [27,28] | |
2003–2004, Cairns; Townsville; the Torres Strait | DENV-2 | 999 | 895 | 35 (3.91) | 26.34 | 4 (0.45) | 2 (0.20) | [27,29,30] | |
2005, the Torres Strait; Townsville | DENV-4 | 116 | 76 | 0 | 3.04 | 0 | 0 | [27,31] | |
2006, Townsville; Cairns | DENV-3; -2 | 76 | 37 | 0 | 1.95 | 0 | 0 | [27,31] | |
2007, Townsville | DENV-3 | 119 | 47 | 0 | 2.93 | 0 | 0 | [27,31] | |
2008–2009, Port Douglas; Mossman; Townsville; Cairns | DENV-3; -3; -3, -1; -2, -3 | 1,314 | 1,042 | 73 (5.56) | 26.58 | 6 (0.46) | 1 (0.11) | [26,27,31,32] | |
2010–2011, Cairns; Townsville | DENV-1, -2, -3, -4; -1, -2, -3 | 474 | 148 | - | 10.94 | 0 | 0 | [31,33] | |
2012, Cairns; Townsville | DENV-1, -2; -1, -2 | 244 | 28 | - | 5.30 | 0 | 0 | [31] | |
2013, Port Douglas, Mossman; Cairns | DENV-3; -1 | 490 | 222 | - | 10.45 | 0 | 0 | [31,34] | |
2014, Cairns; Innisfail; Port Douglas; Charters Towers; Townsville | DENV-1; -1; -3 | 395 | 182 | - | 8.32 | 0 | 0 | [31,34] | |
2015, Cairns, Tully, Innisfail, El Arish, Townsville | DENV-1; -2 | 284 | 62 | - | - | 0 | 0 | [35,36] | |
Florida | 2009, Key West | DENV-1 | 63 | 27 | 0 | 0.3 | 0 | 0 | [37,38] |
2010–2011, Key West; Broward; Miami-Dade Counties | DENV-1, -2 | 257 | 65 | 0 | 1 | 0 | 0 | [37–42] | |
2011, Miami-Dade, Martin, Hillsborough, Palm Beach Counties | DENV-1, -2 | 68 | 7 | - | - | - | - | [43,44] | |
2012, Miami-Dade, Seminale, Osceola Counties | DENV-1, -4, -2, -3 | 139 | 3 | 0 | 0.7 | 0 | 0 | [39,41,45] | |
2013, Martin, Miami-Dade Counties | DENV-1, -4, -3, -2 | 149 | 23 | 6 (3.87) | 0.7 | 0 | 0 | [39,41,46,47] | |
2014, Miami-Dade County | DENV-1, -2, -3, -4 | 51 | 6 | 0 | 0.2 | 0 | 0 | [39,41,48] | |
2015, Broward County | DENV-1, -2 | 85 | 1 | - | - | - | - | [49] | |
Singapore | 2000, Tampines regional centre, Geylang, Marine Parade | DENV-1, -2, -4, -3 | 673 | 402 | 572 (0.85) | 9.3 | 10 (1.5) | 2 (0.30) | [50,51] |
2001, Toa Payoh, Kallang, Hougang, Yishun, Novena | DENV-2, -4, -1 | 2,372 | 2,064 | 1,850 (0.78) | 46.7 | 6 (0.30) | 4 (0.17) | [51,52] | |
2002, Bukit Batok; Geylang; Novena; Sengkang, Jurong Ouest; Woodlands | DENV-2, -1, -3, -4 | 3,945 | 3,560 | 3,156 (0.80) | 86.2 | 8 (0.20) | 4 (0.10) | [53,54] | |
2003, Ang Mo Kio; Bedok; Hougang; Novena | DENV-2, -1, -3, -4 | 4,788 | 4,542 | 3,734 (0.78) | 108.5 | - | 6 (0.13) | [53] | |
2004, Yishun; Ang Mo Kio; Geylang; Bedok | DENV-1, -2, -3, -4 | 9,459 | 9,297 | 7,716 (0.81) | 223.1 | 168 (1.78) | 9 (0.10) | [9,53] | |
2005, Yishun; Woodlands; Kallang; Toa Payoh; Jurong; Bukit Batok | DENV-1, -2, -3, -4 | 14,006 | 13,818 | 10,504 (75) | 333.1 | 381 (2.72) | 27 (0.19) | [9,55] | |
2006, Bukit Batok, Woodlands, Ang Mo Kio, Pasir Ris, Clementi | DENV-1, -2, -3, -4 | 3,127 | 2,844 | - | 71.0 | 75 (2.40) | 10 (0.32) | [51,56] | |
2007, Bukit Batok; Pasir Ris; Woodlands | DENV-2, -1, -3, -4 | 8,826 | 8,637 | - | 192.3 | 189 (2.14) | 24 (0.27) | [57,58] | |
2008, Hougang, Jurong Ouest, Serangoon, Woodlands, Ang Mo Kio | DENV-2, -1, -3, -4 | 7,031 | 6,631 | - | 145.3 | 84 (1.19) | 10 (0.14) | [59–61] | |
2009, Clementi, Bukit Merah, Hougang, Kallang | DENV-2, -1, -3, -4 | 4,497 | 4,187 | - | 90.2 | 46 (1.02) | 8 (0.18) | [59,60,62] | |
2010, Woodlands, Telok Blangah, Newton, Pasir Ris | DENV-2, -1, -3, -4 | 5,363 | 4,978 | - | 105.6 | 34 (0.63) | 6 (0.11) | [59,60,63] | |
2011, Paya Lebar, Woodlands, Serangoon, Yishun, Pasir Ris, Tampines | DENV-2, -1, -3, -4 | 5,330 | 5,099 | - | 102.8 | 22 (0.41) | 6 (0.11) | [59,60,64] | |
2012, Ang Mo Kio, Bedok, Woodlands, Clementi, Hougang | DENV-2, -1, -3, -4 | 4,632 | 4,369 | - | 87.2 | 30 (0.64) | 2 (0.04) | [60,65] | |
2013, Tampines, Yio Chu Kang; Serangoon area, Bedok, Pasir Ris, Jurong, Choa Chu Kang | DENV-1, -2, -3, -4 | 22,170 | 21,863 | - | 410.6 | 93 (0.42) | 8 (0.04) | [59,60] | |
2014, Chuan Drive; Bukit Panjang, Choa Chu Kang, Hougang, Bukit Timah, Bedok, Sengkang | DENV-1, -2, -3, -4 | 18,326 | 17,812 | 3,665 (20.00) | 335.0 | 20 (0.11) | 6 (0.03) | [66–68] | |
2015, Ang Mo Kio, Bishan North | DENV-2 | 11,298 | - | 2259 (20.00) | - | 12 (0.11) | 4 (0.04) | [67,69] | |
Taiwan | 2000–2001, Tainan City, Kaohsiung City | DENV-2, -4 | 418 | 340 | - | 0.6 | - | - | [70,71] |
2002, Kaohsiung City and Kaohsiung County; Pingtung County | DENV-2 | 5,388 | 5,336 | - | 23.9 | 241 (4.50) | 21 (0.39) | [70,72] | |
2003, Kaohsiung City | DENV-2 | 145 | 86 | - | 0.6 | 2 (23.25) | 1 (1.16) | [70,72] | |
2004–2005, Pingtung City, Kaohsiung City, Kaohsiung City | DENV-1, -3 | 733 | 538 | - | 1.8 | 8 (1.49) | 0 | [70,72] | |
2006, Kaohsiung City; Kaohsiung County; Tainan City; Tainan County; Pingtung County | DENV-3, -1, -2 | 1,074 | 965 | - | 4.7 | 19 (1.97) | 5 (0.47) | [70,72] | |
2007, Tainan City; Kaohsiung City | DENV-1 | 2,179 | 2,000 | - | 9.5 | 11 (0.55) | 1 (0.05) | [70,72] | |
2008, Kaohsiung City; Kaohsiung County | DENV-1 | 714 | 488 | - | 3.1 | - | - | [45,73] | |
2009, Kaohsiung City; Kaohsiung County; Pingtung County | DENV-3 | 1,052 | 848 | - | 4.5 | - | - | [45,73] | |
2010, Kaohsiung City; Taipei City; Tainan City; Tainan County | - | 1,896 | 1,592 | - | 8.1 | - | 2 (0.11) | [73] | |
2011, Kaohsiung City; Pingtung County; Taipei; Penghu county | - | 1,702 | 1,545 | - | 7.3 | 18 (1.05) | 5 (0.29) | [70] | |
2012, Tainan City; Kaohsiung City | DENV-2 | 1,478 | 1,271 | - | 6.3 | 20 (1.35) | 5 (0.34) | [73,74] | |
2013, Tainan City; Pingtung County; Taipei; Greater Kaohsiung; New Taipei City | DENV-1 | 860 | 596 | - | 3.6 | 14 (2.35) | 1 (0.17) | [70] | |
2014, Kaoshiung City; Chiayi City; Pingtung City | DENV-1 | 15,732 | 15,492 | - | 66.2 | 136 (0.88) | 20 (0.12) | [75,76] | |
2015, Tainan City; Kaoshiung City; Pingtung City | - | 42,916 | 42,572 | >44 (0.10) | - | - | 209 (0.49) | [77] |
* serotype known by place is separated by “;”. Dominant serotype, when known, is given in bold font.