Table 1. The expression status of PARP1, γH2AX, BRCA1, and BRCA2 according to the histological type of soft-tissue sarcoma.
Histological type | No. | PARP1 | γH2AX | BRCA1 | BRCA2 |
---|---|---|---|---|---|
positive | positive | positive | positive | ||
Leiomyosarcoma | 20 | 14 (70%) | 13 (65%) | 12 (60%) | 15 (75%) |
Synovial sarcoma | 17 | 15 (88%) | 11 (65%) | 9 (53%) | 14 (82%) |
Undifferentiated sarcoma | 12 | 8 (67%) | 10 (83%) | 6 (50%) | 7 (58%) |
Myxoid liposarcoma | 10 | 1 (10%) | 1 (10%) | 2 (20%) | 2 (20%) |
Well differentiated liposarcoma | 4 | 1 (25%) | 0 (0%) | 2 (50%) | 1 (25%) |
Dedifferentiated liposarcoma | 3 | 0 (0%) | 1 (33%) | 0 (0%) | 0 (0%) |
Ewing sarcoma | 6 | 3 (50%) | 3 (50%) | 2 (33%) | 4 (67%) |
Malignant peripheral nerve sheath tumor | 6 | 2 (33%) | 3 (50%) | 1 (17%) | 2 (33%) |
Angiosarcoma | 6 | 3 (50%) | 5 (83%) | 2 (33%) | 5 (83%) |
Myxofibrosarcoma | 6 | 1 (17%) | 2 (33%) | 2 (33%) | 0 (0%) |
Adult fibrosarcoma | 5 | 2 (40%) | 3 (60%) | 4 (80%) | 1 (20%) |
Epithelioid sarcoma | 4 | 4 (100%) | 3 (75%) | 3 (75%) | 1 (25%) |
Low grade myofibroblastic sarcoma | 4 | 1 (25%) | 1 (25%) | 1 (25%) | 1 (25%) |
Alveolar rhabdomyosarcoma | 3 | 3 (100%) | 3 (100%) | 1 (33%) | 2 (67%) |
Embryonal rhabdomyosarcoma | 2 | 2 (100%) | 0 (0%) | 0 (0%) | 0 (0%) |
Pleomorphic rhabdomyosarcoma | 2 | 1 (50%) | 1 (50%) | 1 (50%) | 1 (50%) |
Spindle cell/sclerosing rhabdomyosarcoma | 1 | 1 (100%) | 1 (100) | 1 (100%) | 0 (0%) |
Clear cell sarcoma | 1 | 1 (100%) | 0 (0%) | 1 (100%) | 1 (100%) |