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. 2016 Sep 19;11(9):e0163193. doi: 10.1371/journal.pone.0163193

Table 1. The expression status of PARP1, γH2AX, BRCA1, and BRCA2 according to the histological type of soft-tissue sarcoma.

Histological type No. PARP1 γH2AX BRCA1 BRCA2
positive positive positive positive
Leiomyosarcoma 20 14 (70%) 13 (65%) 12 (60%) 15 (75%)
Synovial sarcoma 17 15 (88%) 11 (65%) 9 (53%) 14 (82%)
Undifferentiated sarcoma 12 8 (67%) 10 (83%) 6 (50%) 7 (58%)
Myxoid liposarcoma 10 1 (10%) 1 (10%) 2 (20%) 2 (20%)
Well differentiated liposarcoma 4 1 (25%) 0 (0%) 2 (50%) 1 (25%)
Dedifferentiated liposarcoma 3 0 (0%) 1 (33%) 0 (0%) 0 (0%)
Ewing sarcoma 6 3 (50%) 3 (50%) 2 (33%) 4 (67%)
Malignant peripheral nerve sheath tumor 6 2 (33%) 3 (50%) 1 (17%) 2 (33%)
Angiosarcoma 6 3 (50%) 5 (83%) 2 (33%) 5 (83%)
Myxofibrosarcoma 6 1 (17%) 2 (33%) 2 (33%) 0 (0%)
Adult fibrosarcoma 5 2 (40%) 3 (60%) 4 (80%) 1 (20%)
Epithelioid sarcoma 4 4 (100%) 3 (75%) 3 (75%) 1 (25%)
Low grade myofibroblastic sarcoma 4 1 (25%) 1 (25%) 1 (25%) 1 (25%)
Alveolar rhabdomyosarcoma 3 3 (100%) 3 (100%) 1 (33%) 2 (67%)
Embryonal rhabdomyosarcoma 2 2 (100%) 0 (0%) 0 (0%) 0 (0%)
Pleomorphic rhabdomyosarcoma 2 1 (50%) 1 (50%) 1 (50%) 1 (50%)
Spindle cell/sclerosing rhabdomyosarcoma 1 1 (100%) 1 (100) 1 (100%) 0 (0%)
Clear cell sarcoma 1 1 (100%) 0 (0%) 1 (100%) 1 (100%)