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. 1995 Aug;48(8):768–770. doi: 10.1136/jcp.48.8.768

Organophosphates and monocyte esterase deficiency.

E McClean 1, H Mackey 1, G M Markey 1, T C Morris 1
PMCID: PMC502807  PMID: 7560207

Abstract

AIMS--To examine the possibility that monocyte esterase deficiency (MED) could be caused by exposure to organophosphates. METHODS--Pseudocholinesterase, paraoxonase and arylesterase activities were measured in the serum and acetylcholinesterase activity was measured in the red cells of a group of monocyte esterase deficient subjects and compared with the enzyme activities of a control group of monocyte esterase positive subjects. RESULTS--No significant difference was found between the enzyme activities of the monocyte esterase deficient group and the control group for any of the esterases investigated. CONCLUSION--Current or recent exposure to organophosphorus is not the cause of MED.

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Selected References

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