Table 1.
Anthropometric and functional data in patients with COPD according to phenotypes and severity of the disease
| COPD (n=412) | Predominant airway disease (n=222) | Predominant emphysema (n=190) | P-value | Mild COPD (n=284) | Severe COPD (n=128) | P-value | |
|---|---|---|---|---|---|---|---|
| Males/females | 299/113 | 174/48 | 125/65 | 195/89 | 104/24 | ||
| Age | 70±9 | 71±8 | 69±9 | ≤0.05 | 70±9 | 69±8 | ns |
| p/y | 46±27 | 45±29 | 48±25 | ns | 45±28 | 50±24 | ns |
| BMI | 26±5 | 28±5 | 25±4 | ≤0.0001 | 27±5 | 25±4 | ≤0.0001 |
| FEV1(%) | 69±25 | 76±23 | 61±26 | ≤0.0001 | 79±22 | 48±19 | ≤0.0001 |
| FEV1/VC (%) | 52±14 | 57±11 | 46±14 | ≤0.0001 | 58±11 | 39±12 | ≤0.0001 |
| FRC (%) | 120±31 | 110±25 | 132±32 | ≤0.0001 | 107±21 | 150±29 | ≤0.0001 |
| TLC (%) | 105±17 | 100±16 | 110±16 | ≤0.0001 | 100±15 | 116±15 | ≤0.0001 |
| DLCO (%) | 76±23 | 89±16 | 61±16 | ≤0.0001 | 81±21 | 66±22 | ≤0.0001 |
Note: Data are presented as mean ± SD.
Abbreviations: BMI, body mass index (weight/height2); COPD, chronic obstructive pulmonary disease; DLCO%, diffusing capacity of lung for carbon monoxide (% of predicted); FEV1%, forced expiratory volume in 1 second (% of predicted); FEV1/VC%, FEV1–vital capacity ratio; FRC%, functional residual capacity (% of predicted); ns, nonsignificant; p/y, number of daily cigarettes × number of years/20; SD, standard deviation; TLC%, total lung capacity (% of predicted).