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Smoothened inhibitors currently in development
| Drug | Manufacturer | Trials |
|---|---|---|
| BMS-833923 | Bristol–Myers Squibb | CML (NCT01218477) |
| Glasdegib (PF-04449913) | Pfizer | MDS (NCT01842646) |
| LEQ506 | Novartis | Solid tumors, medulloblastoma, and aBCC (NCT01106508) |
| LDE255 | Novartis | MDS (NCT02323139) |
Abbreviations: CML, chronic myelogenous leukemia; MDS, myelodysplastic syndrome; aBCC, advanced basal cell carcinoma.
